21+ Comedy Clubs in San Diego, California

Find 21-and-over comedy clubs in San Diego, California. Browse adult-only venues, show schedules, and ticket links.

American Comedy Co. — San Diego, CA — rated 4.7/5 (3431 reviews) · tickets $29.00 · open mic nights
Mad House Comedy Club — San Diego, CA — rated 4.2/5 (620 reviews) · tickets $18-$36 · open mic nights
National Comedy Theatre — San Diego, CA — rated 4.8/5 (286 reviews) · tickets $15–$35
Comedy Heights — San Diego, CA — rated 4.9/5 (86 reviews) · tickets $5
Finest City Improv — San Diego, CA — rated 4.7/5 (191 reviews) · tickets $5-$16.05
Laugh Factory San Diego — San Diego, CA — rated 3.3/5 (110 reviews) · tickets $22–$40 · open mic nights
Mic Drop Comedy — San Diego, CA — rated 4.8/5 (1491 reviews) · tickets $25–$55 · open mic nights
Mockingbird Improv — San Diego, CA — rated 4.8/5 (205 reviews) · tickets $15-$17 · open mic nights
National Lampoon The Yellow Door — San Diego, CA — rated 4.5/5 (47 reviews) · tickets $15–$30

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