Open Mic Comedy in Greenville, South Carolina

Find open mic comedy nights in Greenville, South Carolina. Browse venues, sign-up info, and schedules.

• The Comedy Zone — Greenville, SC — rated 4.5/5 (1372 reviews) · tickets $25–$55 · open mic nights
• Alchemy Comedy Theater — Greenville, SC — rated 4.5/5 (221 reviews) · tickets $10-$15 · open mic nights

Explore more

• All comedy clubs in Greenville