South Carolina has 6 stand-up comedy clubs across 5 cities, including 3 venues that host open mic nights. Top venues include The Comedy Zone in Greenville, Comedy Cabana in Myrtle Beach, Wit's End Comedy Lounge in North Charleston. ComedyClubFinder lists every comedy club in South Carolina with addresses, ticket prices, and show schedules.

Comedy Clubs in South Carolina

Discover 6 stand-up comedy clubs across 5 cities in South Carolina. 3 venues host open mic nights.

6 venues
5 cities
3 open mic venues

All Comedy Clubs in South Carolina

(864) 603-1583Sunday – Thursday shows are 18+ | Friday & Saturday early shows are 18+ | Friday & Saturday late shows are 21+$25–$55

Stand-Up Comedy in South Carolina

Total Venues
6
Cities Covered
5
Open Mic Venues
3
State Code
SC

South Carolina's burgeoning stand-up comedy landscape offers a distinctive Southern flavor, often characterized by engaging storytelling and observational humor rooted in local experiences. Comedy enthusiasts can find laughs across the state, with key venues like The Comedy Zone in Greenville and North Charleston providing a consistent lineup of touring headliners. For those by the coast, Comedy Cabana in Myrtle Beach delivers a classic club experience, while Wit's End Comedy Lounge offers another intimate setting for performances. The state also fosters a growing open mic scene, with two active opportunities for aspiring comedians to hone their craft. Weekday evenings are typically the best time to catch these developing talents, offering a raw and often surprising glimpse into the local comedic voice. Weekends, conversely, are reserved for established acts and national headliners, promising polished performances. The humor often reflects the state's unique blend of tradition and modern life, delivered with a charm that resonates with both locals and visitors. When planning a night out, it is always advisable to check venue websites for age restrictions and to book tickets in advance, especially for popular weekend shows, to ensure a seat.

Frequently Asked Questions

Why trust this guideto South Carolina comedy clubs

Verified venue data

All 6 venues verified against official websites and Google Business Profiles. We check for closures, address changes, and policy updates quarterly.

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Star ratings and review counts are sourced directly from Google Places — not estimated or fabricated. Only venues with a Google Business Profile listing are shown.

Last reviewed: April 2026

ComedyClubFinder reviews and updates venue data quarterly. Closed venues are removed; new venues are added as they open. If you spot an error, use the "Report an issue" link on each venue page.

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