Helium Comedy Club - Buffalo is a contemporary entertainment venue that bring stadium-sized talent to an intimate theater on a weekly basis.
Photos via Google Maps
30 Mississippi Street, Buffalo, NY 14203
Helium holds its Open Mic Night on SELECT Wednesday nights at 7PM, open to both new talent and seasoned comics. Comics signing up should prepare at least 3 minutes of material. Sign up in-person the night of the event by 6PM.
Always a fun night. I totally would recommend paying a few extra dollars and pay for the front seats. The view unobstructed and comedy right in your face feet away. You might even get caught up in the jokes 😃🤣 too. They do have a drink minimum and even with that not bad pricing for a fun night. I do love the meet and greets too. But live life with a laugh and you will see me again here ❤️ it!
My two friends and I attended the wicked drag brunch on March 8th. We were not allowed to order drinks at the bar, and were told we had to put drink orders in before food. We waited for over 30 minutes until we were given our drinks and were able to put our food in. The show ended over an hour later and we still had not received our food. The manager originally was not going to let us cancel our order, but after the show ended and people were leaving we were able to cancel our food order. When we got our bill, it was almost $100 for five drinks, although we were originally told our bill would be discounted because of the long wait time. While I do not at all fault our waitress, who was doing everything she could to do her job despite the clubs severe under planning, the club did not accommodate the large crowds, and was extremely overpriced. We left feeling angry at our overpriced drinks, and very hungry after being at a show for almost two hours without being served our food.
Ample parking is conveniently available in the lots across from the First Niagara Center on Perry St.
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Last reviewed: April 2026
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