DNA's Comedy Lab
DNA’s Comedy Lab is dedicated to helping comics find venues, helping bookers find comics and helping fans find their favorite funny people.
Photos via Google Maps
Location
1001 Center St, Santa Cruz, CA 95060, Santa Cruz, CA
Open Mic Night
Wednesday is open mic night.
Google Reviews
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Went to see the show with headliner Craig Low and it was an awesome show! I dont drink anymore, however, I noticed they have a great selection of beer and other drinks to enjoy during shows. The owner of the "comedy lab" did some standup as well and it was very enjoyable! I was laughing so much, I'll be sure to be back!! I'm so thankful we finally have a place for great standup in Santa Cruz.... it was about time!
DNA's Comedy Lab draws some surprisingly big names. The theater hosts a variety of cool events. The openers are always pretty strong. And also, the staff's really friendly. What a great place to spend a Thursday, Friday or Saturday night.
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Last reviewed: April 2026
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